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It is an important co-substrate of a large class of enzymes and regulates gene expression by interacting with important transcription factors. This property helps to fluidize fatty secretions increasing immune access to infection. Immunity In Depth Linus Pauling Institute Oregon State University It can also protect against disease and may help prevent anemia and gout. Vitamin c and immunity . Ascorbic acid AA also known as vitamin C was initially identified as the factor preventing the scurvy disease and became very popular for its antioxidant properties. Vitamin C enhances the mucolytic effect. The target population was the general population. While the Recommended Dietary Allowance RDA for vitamin C is 75 mg per day for women and 90 mg per day for men 4 many people like to take hyper-doses or mega-doses to supercharge their immunity. Vitamin C is a water-soluble vitamin that acts as an antioxidant and is involved in the synthesis of collagen and other important compounds